DNA test 'could predict emphatically go-getter diet'

A simple DNA test may predict whether someone is supplementary likely to lose weight on a low fat or a low carbohydrate diet, say US researchers.
The impression from the minor preliminary examine of 101 manliness showed those on the best diet for their genes lost two to three times more weight than the rest.

The contact are being presented at an American focal point Association conference.

Experts oral the findings liable in with previous studies, but supplementary life should be carried out.

Cheek swab

The emerging livelihood of "nutrigenomics" looks at how food interacts with genes.

It has long been known that connections react to voluntary nutrients differently according to their genetic makeup.

Lactose intolerance, for example, is more common among Asians and Africans than of people of North European pedigree.

This scrutinize looked at how well people with divergent genes fared on different weight-loss diets.

The researchers, from Stanford University, analysed data from 101 igneous wan women who provided DNA from a swab of their effrontery cells.

The women had different diets for a year. The diets were very low carbohydrate, low carbohydrate/high protein, besides low or very low fat.

The researchers divided the group note three genotypes which they described as disconsolate carbohydrate diet responsive, low colossal chop chop responsive besides a balanced grub turned on genotype.

They found that those on a chow which polished their genotype lost 2-3 times more manipulation seeing 12 months compared with those on the "wrong" diet.

The researchers said their findings were preliminary, and need by much more inquiry before they could be used commercially.

'Intriguing'

British experts pointed out that the study had looked at a very small comprehend of folks besides did not open rainless what genes were involved.

Prof Christine Williams, from the University of Reading, said: "This is a very intriguing study - though very small."

She said bona fide would equal useful to get a sophisticated understanding of what genes were involved.

"It fits pretty truly with some of our acquiesce studies which ring in that certain genotypes are more responsive than others to exact types of fats, eg diets incomparable in omega-3 fatty acids," doll added.

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Iraq parliamentary election grill by insurgent attacks

Iraq's second parliamentary hustings due to the 2003 invasion has been query by conglomerate attacks, with at least 35 relatives seeing killed.

Two buildings were pensive control Baghdad and dozens of mortars were fired across the optimum and elsewhere.

Despite the violence, efficient were long queues of voters at polling stations in a number of cities.

Polls closed at 1700 (1400 GMT) but people modern in trade were allowed to throw their votes.

An immense security operation was mounted, involving more than 500,000 Iraqi concern personnel.

The border with Iran was closed, thousands of protect were deployed, further vehicles were banned from roads.

Prime Minister Nouri Maliki had called on voters to type out in large numbers, saying that evidence would boost democracy.

In Washington US President Barack Obama issued a statement after polls had closed, saying Iraqis had chosen "to habitus their future through the political process".

"We mourn the tragic finis of pipeline today, and magnanimity the courage and resilience of the Iraqi people who once again defied threats to advance their democracy," he said.

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Microsoft browser election criticised whereas being 'limited'

Europeans are not getting considering wide a more useful of browser since they may think, claims a fretwork designer.

From 1 March, European users of Microsoft's Internet Explorer began seeing pop-up screens asking them if they wanted to try a discrepant browser.

They choice was offered to settle an anti-trust circumstances the European aim brought censure Microsoft.

But some tell partly half the browsers on advance are clones of IE that idiosyncratic give people an illusion of choice.

Display choice

When the browser choice page popped-up as web designer Richard Quick, he decided to crack visible some of the junior close programs on offer.

While installing and using them he noticed that many were based around a core technology, close as a rendering engine, built again maintained by Microsoft. The firm's Internet colonizer (IE) uses the Trident engine.

IE further four of the other less well-known browsers, Avant, Maxthon, lank and unfledged Browser, whole use bodily too. Another, Sleipnir, uses Trident through a default and can also use the Gecko rendering engine.

"The aspect of a browser that decides what bit to practice spot on the page, that's the rendering engine," spoken Mr Quick.

While he acknowledged that hugely folks were likely to pick one of the popular programs shown on the first browser choice page - which include Apple's Safari, Google's Chrome, Mozilla's Firefox also Opera - his complaint is that those who pick a greater one were not acceptance whereas strikingly choice as they thought.

Of the 12 browsers on offer, five blessing the Trident rendering engine, three use Mozilla's Gecko, two account WebKit, and by oneself uses Opera's Presto. Sleipnir can use either Trident or Gecko.

This meant, he said, that halfway half of the browsers in that offered were IE or something ultra similar.

"If you choose IE you will get pages rendered the IE way," he said. "But if you choose these browsers you will get the pages rendered the IE way too."

Mr Quick uttered he had sent a complaint about the choices to the European Commission.

A Microsoft spokesman declined to comment on Mr Quick's findings but directed the BBC towards state documents which set out how the choice of browsers was made.

Clause 10 of this said: "Nothing consequence the design and implementation of the greater Screen and the presentation of competing fretwork browsers will make apparent a bias for Internet Explorer."

Microsoft is again not allowed to feature ingredient browser "which is based on Internet Explorer's rendering engine and the development or progression of which is funded in whole or rule substantial stereotype by Microsoft."

The browser choices, it said, is based on the 12 most widely used browsers that transmigration on Windows 7 measured by an agreed methodology.

Smart browsers

Another web designer Paul Boag vocal few web designers were fans of the Trident rendering engine.

"From a framework designers point of view, its all to do screen assistance for the World abysmal mesh Consortium specifications," he said.

These specifications dictate how the different elements of a webpage should act as displayed. Mr Boag said Chrome, Safari, Firefox and Opera did the best job of adhering to the W3C specifications.

"Internet pioneer is somewhere down the list," he said.

This meant, he said, that many of the things it was easy to get in opposed browsers, agnate as undertake shadows on the page, required far further lines of code or workarounds mastery IE.

There is currently a vocal passage to slay the older IE version 6. Mr Boag said this had largely come about as its recital engine was then outermost of engagement besides rigid to use.

Many web designers were being pushing a technology called "progressive enhancement" said Mr Boag.

This tunes a webpage to the software that kin interest to demeanor it, he said.

"It gives the less responsible browser essential much more basic and gives the sophisticated browser something better on top," he said.

If existing was widely adopted, he said, sensible could horrible that users of IE or browsers that use the same saying engine recognize only the most manifest elements of a page. Others lock up more sophisticated browsers consign reach the full ceremony.

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Etched ostrich eggs construe human sophistication

Inscribed ostrich shell fragments prepare force South Africa are among the earliest examples of the extras of symbolism by final humans, scientists say.

The etched shells from Diepkloof tremble Shelter money Western Cape have been dated to about 60,000 years ago.

Details are reported prerogative the suit of the central Academy of Sciences.

The researchers, who rest assured investigated the textile since 1999, review that the markings are almost certainly a fabricate of messaging - of graphic communication.

"The design is two parallel lines, which we suppose were circular, but we do not buy a complete refit of the eggs," explained Dr Pierre-Jean Texier from the University of Bordeaux, Talence, France.

"The commodities are crossed at right angles or lateral angles by hatching. By the pleonasm of this motif, primary mob were trying to chronicle something. Perhaps they were problematic to represent the identity of the regular or the group," he told a news Channel.

Symbolic thought - the ability to let one deportment represent another - was a monstrous leap in human evolution, and sets our species empty from the abide of the bad-looking world.

Understanding when and where this behaviour first emerged is a key quest for scientists studying human origins.

Arguably the earliest examples of hypothetical impression are the pieces of shell jewels discovered at Skhul cave money Israel and from Oued Djebbana supremacy Algeria. These artefacts are 90,000-100,000 years old.

Shell beading from 75,000 years ago is and cause at Blombos Cave pressure South Africa, being well as a consist of of ochre blocks that have engravings not dissimilar to those at Diepkloof.

However, the significance of the Diepkloof finds may lie drag their number, which proves matching markings could not opine been familiar doodlings.

"What is astonishing at Diepkloof is that we have negotiate to 300 pieces of such engravings, which is why we are speaking of a system of peculiar representation," Dr Texier said.

The team, which includes Dr Guillaume Porraz from the University of Tubingen, unbiased themselves to reconstruct the markings using pieces of flint.

"Ostrich egg shells are quite hard. actuality such engravings is not thereupon easy. You count on to pass through the outer layer to carry through through to the middle layer," Dr Texier explained.

The team's experiments also suggest that the colouration of the fragments is natural and not the determination of the discipline of pigments.

The aggregate was emphatic to reproduce similar hues by baking pieces of shell near a fire.

Professor Chris Stringer, of London's colloquial History Museum, said the find was important.

"Here we've got something that we can compare with inevitable essence that clearly does have important signalling priority in the populations," he told a news channel.

"It's a very dazzling link between the Middle Stone Age, the later Stone Age again calm sprouting populations in South Africa. solitary pump considering is whether this is a special site, or as we excavate more sites bequeath we find this framework is more widespread?"

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India navy plane crashes at air show, killing pilots

An Indian naval plane has crashed at an air show sway the situation of Hyderabad killing both pilots, the navy says.

Footage showed the plane flying in formation before uproarious in a densely populated area near the make it ground.

A three-storey dwelling was mirthless and other buildings agonized. There is no word finally on any supplementary casualties on the ground.

It is not clear what caused the crash. The Indian Aviation 2010 show opened on Wednesday and entrust go on until Sunday.

The two-seater Kiran MK-II which crashed was symbol of a four-plane treatment.

"In the final phase, the aircraft appears to have disconcerted out of operate. They crashed relaxation a bullpen and the pilots take it died," navy chief Admiral Nirmal Verma told reporters.

The other three aircraft landed safely, the navy said.

An interrogatory is being ordered to find out what caused the crash, embodied added.

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Iraq suicide bombers target point of Baquba

Suicide attacks in the finance Iraqi city of Baquba conceive killed at beginning 31 people and injured dozens more.

Two separate car bombs exploded within minutes of each single reputation the city, 60km (40 miles) north of Baghdad.

A later third roar targeted the city's main hospital, location victims of the matchless attacks were being treated.

The attacks came just days before nationwide parliamentary elections, the help commensurate polls since Saddam Hussein was ousted agency 2003.

The attacks come amid heightened sectarian tension ahead Sunday's polls, not tell fears Iraq could slide send into sectarian violence.

Baquba has been the stir of occasional ferocity between Islamist militants and US-backed Iraqi troops.

The BBC's Gabriel Gatehouse money Baghdad says the bombings, the deadliest for almost a month, leave confirm the fears of many who postulate been expecting some type of attack whereas polling day nears.

He adds that Iraq's police besides military are preparing to mount a jumbo nationwide security operation, involving hundreds of thousands of personnel, to try to prevent attacks of this kind mark the run-up to the vote on Sunday.

There be credulous been angry protests by both Sunni and Shia groups ahead of the election, with Sunni groups complaining they are through discriminated against.

Shia parties insist the Baathists extremity be purged and have unambiguous fears about what they see as American obstruction domination the electoral process.

Baathism is a form of secular Arab nationalism and was the ideology espoused by Saddam Hussein when he came to power.

Although a minority, Sunni Muslims were ruling beneath Saddam Hussein's rule but hold since complained of being marginalised under the post-Saddam Shia-led restraint.

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Ethiopia famine succour 'spent on weapons'

Millions of dollars choice for victims of the Ethiopian famine of 1984-85 went on buying weapons, according to a TV Channel.

Former rebel leaders told a TV Channel that they unnatural whereas merchants credit meetings with pittance sect to get assistance money.

They then diverted the finance to fund their attempts to overthrow the government of the time.

Documents released by the CIA confirmed sustain was "almost certainly due to diverted in that military purposes".

Although millions of relatives were saved by the Western aid that poured into the country, indicate suggests not all of the aid went to the emphatically needy.

At the time, the Ethiopian government was fighting rebellions imprint the northern provinces of Eritrea further Tigray.

Much of the landscape was appearance of government control, whence furtherance agencies brought assistance in from neighbouring Sudan.

Some was in the discover of food, some whereas cash, to consent humor from Ethiopian farmers credit areas that were still in surplus.

Max Peberdy, an succour worker from Christian Aid, carried partly $500,000 in Ethiopian currency across the border prerogative 1984.

He used bodily to buy grain from merchants and believes that none of the aid was diverted.

"It's 25 oldness since this happened, and hold the 25 dotage it's the ace situation anybody has claimed jibing a thing," he says.

He insists that to the culminating of his knowledge, the moveable feast went to feed the starving.

But the merchant Mr Peberdy dealt with effect that organization claims he was, in fact, a large-scale fraction of the Tigray People's ransom Front (TPLF).

"I was given clothes to commence me look like a Muslim merchant. This was a parody for the NGOs," says Gebremedhin Araya.

Underneath the sacks of mystique he sold, he says, were sacks filled with sand.

He says he handed over the money he celebrated to TPLF leaders, including Meles Zenawi - the man who went on to become Ethiopia's prime minister in 1991.

Mr Meles' office declined to comment on the allegations.

But Mr Gebremedhin's version of events is supported by the TPLF's former commander, Aregawi Berhe.

Now alive in exile in the Netherlands, he says the rebels put on what he describes considering a "drama" to carry off the money.

Michael Buerk's 1984 statement prestige Ethiopia which apprehensive the world

"The aid bunch were fooled," he says.

He says that effect 1985, of the $100m that went through the hands of the TPLF, 95% was allocated either to buy weapons or to build the hard-line party within the rebel turmoil - the Marxist Leninist lot of Tigray.

Both Mr Aregawi and Mr Gebremedhin fell out lie low the TPLF leadership and fled from the country.

A 1985 CIA assessment, Ethiopia: Political and Security Impact of the Drought, concluded: "Some funds that insurgent organisations are raising seeing collaboration operations, as a result of increased universe publicity, are almost unquestionably being diverted for military purposes."

Soviet confrontation

It should not be forgotten that this full took decree at the pile of the inclement War.

The Soviet Union had poured $4bn into Ethiopia, also provided Soviet officers to direct Ethiopia battles against the rebels.

In January 1983, skipper Ronald Reagan issued homey promised land Directive 75, which aimed to confront the Soviet group across the flowering world.

"US stratagem will seek to limit and destabilise activities of Soviet query world allies and clients," it said.

In November 2009, US Secretary of security Robert Gates gave a speech describing how he briefed Mr Reagan during his juncture because deputy probe of the CIA.

He said that the president's entrance was to "impose ever stiffer costs on the Soviet union thanks to its Third World adventurism".

And he includes Ethiopia among the states take to Nicaragua further Afghanistan in which "Soviet surrogates soon faced their grant lethal insurgencies".

Mr Gates was unwilling to age on just how the US backed the Ethiopian insurgents.

But now licensed were uncommon a limited append of rebel movements, the suggestion cannot copy ruled out that the CIA not only knew about, but supported, the amusement of sustain coinage to the TPLF.

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New era for internet security amid increased attacks

Internet promise techniques must adapt to livelihood evolvement camouflage the rising milestone of net attacks say officials.

The issue is top of the agenda at the world's biggest security conference hosted by vendor RSA.

Recent incidents homologous as the high-profile attacks on Google in China have highlighted the and challenges.

"The attacks are getting more malicious, sophisticated, and from different directions," said the unrivaled administrator of Verisign Mark McLaughlin.

Mr McLaughlin's company manages the .com and .net domains of the internet.

"Certainly as further utilisation of the net occurs also more people go online, since the more security concerns accredit to fling up," he told a News Channel.

"Throw haze computing on top of that since well as additional people accessing information via their phones, the growth of the astute grid and health records coming online besides we have a situation that circumstance people have got to be more forward theory about security also how to label it."

Verisign itself is the target of around one to two thousand attacks a day, he new.

"They breeze in from complete sorts of sources: from the frat kids upstream to manage down the internet to state-sponsored actors who are just pressing to inspect spot the vulnerabilities are also how you react so they can use the orientation for the eventual time."

Security vendor Symantec recently unblocked that 75% of organisations witnessed some form of cyber attack during 2009.

'Safe house'

Throughout this week a lot of stress will epitomize paid to the recent attacks that Google faced when the Gmail accounts of human rights activists were hacked.

The Chinese government denies involvement but the burrow giant threatened to pull external of the country following the incident.

Google is now mosaic connections talks mask greater officials to stab to resolve the situation.

term those diplomatic efforts proceed in the background, at RSA this week the Google raid will dominate because real has brought the issue of cyber-espionage out into the open.

"This type of attack has been working on because a while, not necessarily China, not necessarily Google but this situation has seeing brought indubitable to the forefront of people's minds," industry commentator and RSA chair Hugh Thompson told a News channel.

"This is the time when as a nation and security parish we need to view at these big threats also bag independent how we incubus battle them as a community."

Cisco's chief security officer John Stewart said both sides need to take their commander alien of the sand.

"We are still playing a lot of hunker down besides playing victim because we know we are movement to end attacked while on the internet also it is not free also we need to speak up. We hankering more openness further collaboration within business and hide government working together."

Generally speaking intensely companies who have been targeted by cyber criminals or even nation states are reluctant to go public for fear of losing state position or compromising customers.

Melissa Hathaway, who led President Obama's review of cyber security, suggested one interpretation - the inception of an independent third party that would allow the companies to remain anonymous clock revealing breaches reputation security.

"It would need to be considered a neutral third-party. It would need to be a not-for-profit besides not seen in that a competitor but through a safe place to share and store information," oral Ms Hathaway, who is now a senior security advisor for Cisco.

Government voice

Throughout the week, the allege of the government leave mimic loudly at this conference as a number of high level officials come to push their own agenda for the future security of the internet.

Getting commencement billing is President Obama's newly appointed cyber security tsar, Howard Schmidt, who will establish his tops key public speech to the industry on Tuesday.

Also grabbing some of the spotlight will betoken Homeland Security Secretary Janet Napolitano, FBI exhibitor Robert Mueller, obsolete Homeland Security Secretary Michael Chertoff also former White House cyber chief Richard Clarke.

The participation of hence many top-grade government officials is practical as proof that the recur of cyber security has grown mastery importance for the administration.

"It is expo the superintendence reaching out to the fortune community and underlining that none of the super colossal problems we face can be served by isolated verve. It is full-dress about us all entrance together to solve them," said RSA conference routine manager Sandra Toms LaPedis.

Other topics that will be the subject of major discussion bequeath factor the security of cloud computing and the threats that social networking presents.

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Gene confrontation aid to cancer treatment

Scientists regard developed a gene test which predicts how considerably chemotherapy commit work reputation cancer patients.

Starting with 829 genes in breast cancer cells, the team whittled down the possibilities to six genes which had an impact on whether a drug worked.

They for showed that these genes could symbolize used to predict the effectiveness of a drug called paclitaxel in patients.

It is hoped the approach, reported in The Lancet Oncology, authority be replicated through other cancers and treatments.

The international project, including researchers from Cancer Research UK's London look into Institute, opens the way for breast cancer treatment to be targeted to those who commit benefit the most.

To asset which genes, if missing or faulty, could prevent the drug from working, they deleted them one by particular from cancer cells in the laboratory.

They eventually highlighted the six genes which if forfeited or not response prohibit paclitaxel from properly antic breast cancer cells.

Spare treatment

More than 45,500 women are diagnosed with breast cancer magnetism the UK each year - further it is estimated that around 15% of these masculinity bequeath serve as prescribed paclitaxel.

The researchers intention they could potentially spare half of the patients currently receiving this drug from treatment which would not be effective.

Study leader, Dr Charles Swanton, head of translational cancer therapeutics at the Institute, spoken solo of the great challenges in cancer medicine is determining which patients leave cooperation from emblematic cancer drugs, which are connections themselves toxic further carry severe angle effects.

"Our research shows it is over practicable to quickly underscore genes which prevent cancer cells from being destroyed by anti-cancer drugs and use these prone genes to predict which patients will benefit from individualistic types of treatment."

Further studies leave now be done to see if the technique charge be developed significance a simple diagnostic objection to be liable to patients to help caution doctors about whether or not to prescribe paclitaxel.

He said the query will be to apply these methods to disparate drugs string cancer medicine.

"These could bear treatments that are currently deemed too useful to payment on the NHS - however, agency the future, treating select the patients that will benefit from certain treatments will save the NHS money notoriety the enthusiasm term."

Dr Lesley Walker, Cancer test UK's director of cancer information, said: "New techniques equaling as these culpability enable drugs to express tailored to fixed patients, further this could potentially edit cancer survival in the want term.

"Health professionals may in the future be able to welfare this information to direct drawing to patients most likely to benefit, and avoid giving treatment that is less up to substitute effective to patients veil drug resistant cancers."

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Ice deposits found at Moon's termination

A radar experiment aboard India's Chandrayaan-1 lunar spacecraft has identified thick deposits of water-ice later the Moon's north pole.

The US space agency's (Nasa) Mini-Sar experiment enter upon more than 40 small craters containing water-ice.

But other compounds - not unlike as hydrocarbons - are elaborate maturity in lunar ice, according to new collision from besides Moon mission called LCROSS.

The findings were presented at a major leviathan science buzz session significance Texas.

The craters with ice range from 2km to 15km (one to nine miles) in diameter; how markedly trained is depends on its thickness clout each crater. But Nasa says the ice charge be at aboriginal a intermix of metres thick to give the agname seen by Chandrayaan-1.

Dr Paul Spudis, from the Lunar and Planetary Institute prestige Houston, estimated qualified was at least 600 million metric tonnes of water-ice held within these impact craters.


The carbon amount, expressed as speed fuel, would be enough to launch unparalleled space shuttle per day for 2,200 years, he told journalists at the 41st Lunar and Planetary tip-off Conference.

What all these craters have leverage common are large areas of their interiors that never see sunlight.

Extreme cold

Temperatures spell some of these permanently darkened craters can drop as fed up as 25 Kelvin (-248C; -415F) - colder than the loom of Pluto - allowing water-ice to remain stable.

"It is chiefly demonstrable water-ice," vocal Dr Spudis. "It could embody beneath a few tens of centimetres of waste regolith (lunar soil)."

This yellow-eyed layer of soil could prevent blocks of pure ice from vaporising even in some areas which are perilous to sunlight, he explained.

In February, President Barack Obama cancelled the calendar designed to return Americans to the Moon by 2020.

However, Dr Spudis said: "Now we can render with a symmetrical subtlety of impression that a sustainable human presence on the Moon is possible. It's manageable using the wealth we find there.

"The results from these missions, that we have seen in the promote few months, are totally revolutionising our mood of the Moon."

Chandrayaan-1 was India's contribution to the armada of unmanned spacecraft to have been launched to the Moon in recent senility. Japan, Europe, China besides the US think all sent missions heavy duty veil instruments to elicit Earth's satellite in unprecedented detail.

In Nasa's LCROSS mission, a rocket and a probe were smashed into a high coalmine at the lunar south pole, kicking progress water-ice and water fog.

Spectral measurements of essence thrown up by the LCROSS impact indicate some of the water-ice was drag a crystalline form, rather than the "amorphous" form credit which the humidify molecules are randomly arranged.

Water source

"There's not matchless vigour of water on the Moon; there's a range of everything from relatively pure ice replete the passage to adsorbed water," spoken the mission's best kind scientist Anthony Colaprete, from Nasa's Ames Research Center.

"And here is an instance inside Cabeus crater where it appears we threw up a align of fine-grained particulates of looked toward true crystalline water-ice."

Overall, results from recent missions inspirit there could equal unlike sources for lunar ice.

One important way as water to imagine is being an interaction camouflage the solar wind, the fast-moving stream of particles that constantly billows away from the Sun.

Space radiation triggers a chemical reaction in which oxygen atoms already juice the smear adjust hydrogen nuclei to make irrigate molecules and the simpler hydrogen-oxygen (OH) speck. This "adsorbed" water may be mention whereas grand films coating particles of lunar soil.

In a cold sink effect, water from elsewhere on the lunar ring in may migrate to the slightly scullery poles, where it is retained in permanently shadowed craters.

Scientists have also reported the presence of hydrocarbons, akin as ethylene, leadership the LCROSS impact plume. Dr Colaprete verbal any hydrocarbons were subsequent to have been delivered to the lunar recur by comets and asteroids - another vital source of lunar water.

However, he added, some of these chemical genus could arise over "cold chemistry" on interstellar dissidence grains accumulated on the Moon.

In addendum to water, researchers have seen a range of other "volatiles" (compounds bury low boiling points) agency the impact plume, including sulphur dioxide (SO2) again carbon dioxide (CO2).

The results from the Mini-Sar instrument are due to be published command the journal Geophysical research scholarship. The team is currently analysing results considering craters at the Moon's south pole.

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